基因驱动为何能打破孟德尔遗传的 50% 传递规律?
Why can a gene drive break Mendel's 50% inheritance rule?
基因驱动借助 CRISPR 在杂合个体中把目标等位基因复制到同源染色体上,使子代几乎全部携带该基因,从而让性状在野生群体中快速扩散,也带来生态伦理风险。
A gene drive uses CRISPR to copy the target allele onto the homologous chromosome in heterozygotes, so nearly all offspring inherit it, spreading a trait rapidly through wild populations and raising ecological-ethics concerns.
难度 专业 · 适合 高中(15-18)
CC BY 4.0 · 来源待核验 · Source pending review
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出处备注:此条未指向带版次的可引用著作(通识性内容、机构文件或未展开的英文书名),本库不提供独立书目出处;如需精确引用,需由编辑补全具体篇目与版次。
Nature Biotechnology
Nature Biotechnology
#基因驱动 #CRISPR #伦理
CRISPR-Cas9 实现基因编辑的基本步骤是什么?
What are the basic steps by which CRISPR-Cas9 performs gene editing?
向导 RNA 引导 Cas9 蛋白识别互补的 DNA 序列,Cas9 像分子剪刀在特定位点切开双链,细胞修复时引入插入、缺失或外源片段,从而实现敲除或定点修改。
A guide RNA directs Cas9 to a complementary DNA site where Cas9 cuts the double strand like molecular scissors; cellular repair then introduces insertions, deletions or donor sequences, achieving knockout or precise edits.
难度 进阶 · 适合 大众
CC BY 4.0 · 已核验 · Verified 2026-08-23
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Lewin's Genes XII,Jones & Bartlett Learning,2018
Lewin's Genes XII, Jones & Bartlett Learning, 2018
#CRISPR #基因编辑 #Cas9
重组胰岛素是如何利用转基因技术生产的?
How is recombinant insulin produced using transgenic technology?
把人胰岛素基因克隆到质粒并导入大肠杆菌或酵母,让工程菌大量表达人胰岛素,再纯化制成药物,避免了从动物胰脏提取的供应与过敏问题。
The human insulin gene is cloned into a plasmid and introduced into E. coli or yeast, which mass-produce human insulin that is purified into medicine, avoiding supply and allergy issues of animal-derived insulin.
难度 进阶 · 适合 小学低段(6-8)
CC BY 4.0 · 来源待核验 · Source pending review
来源 · Source
出处备注:著录仅给书名,无版次与年份;同一书名常对应多个版次,不臆测具体版本。
《生物技术》教材
Biotechnology (Smith)
#重组胰岛素 #转基因 #生物制药